Joe Biden's back story, which I didn't know (h/t Atrios):
Biden made it work. He won, and became the youngest senator. But before he could even take office, Neilia, his two sons, and their baby daughter were in a brutal car accident in Delaware. Neilia and the baby were killed and the boys, Beau and Hunter, were badly injured. Biden stayed by their side during their recovery and initially refused to return to D.C. to take his Senate seat, acquiescing only after then-Majority Leader Mike Mansfield pushed him to take it.
Biden vowed to remain a fixture in his sons' lives. Valerie became their surrogate mother, and Biden began the daily commute from Wilmington to Washington that made him an Amtrak champion for life. Even after Biden met and married his second wife, Jill, five years later, he didn't surrender the back-breaking schedule. "Kids keep a thought in their heads for 12 hours," he says at one campaign stop. "They aren't gonna keep it for 24 hours."